I just cleared a dungeon on floor 13. Puffballs are so good for confusing monsters up front so that they don't flow out of the dungeon en-mas giving you more time to back up and line up your AOE spells (Fleshmithing putrification) en-masse. Plus, with my throwing skill, the puff balls are hitting upwards of 70 damage, which added in with the hyperborean mittens and I single puffball is doing 100's of damage. And I my fair share of them back from the zoo. I still have about 130. Love those things.